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Cellosaurus ID8-Luc2 (CVCL_IU16)

[Text version]
Cell line name ID8-Luc2
Synonyms ID8luc2
Accession CVCL_IU16
Resource Identification Initiative To cite this cell line use: ID8-Luc2 (RRID:CVCL_IU16)
Comments Transfected with: UniProtKB; P08659; Firefly luciferase (with optimized codon usage for mammalian expression).
Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_IU14 (ID8)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=25992288; DOI=10.1186/s40425-015-0060-6
Liao J.B., Ovenell K.J., Curtis E.E.M., Cecil D.L., Koehnlein M.R., Rastetter L.R., Gad E.A., Disis M.L.
Preservation of tumor-host immune interactions with luciferase-tagged imaging in a murine model of ovarian cancer.
J. Immunother. Cancer 3:16.1-16.9(2015)

PubMed=26676113; DOI=10.1186/s40425-015-0102-0
Baert T., Verschuere T., Van Hoylandt A., Gijsbers R., Vergote I., Coosemans A.
The dark side of ID8-Luc2: pitfalls for luciferase tagged murine models for ovarian cancer.
J. Immunother. Cancer 3:57.1-57.5(2015)

PubMed=27235858; DOI=10.1016/j.ygyno.2016.05.028
Hernandez L., Kim M.K., Lyle L.T., Bunch K.P., House C.D., Ning F., Noonan A.M., Annunziata C.M.
Characterization of ovarian cancer cell lines as in vivo models for preclinical studies.
Gynecol. Oncol. 142:332-340(2016)

Cross-references
Encyclopedic resources Wikidata; Q54897295
Entry history
Entry creation03-Mar-2017
Last entry update29-Jun-2023
Version number6