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Cellosaurus ZR75T (CVCL_IW49)

[Text version]

Cell line name ZR75T
Accession CVCL_IW49
Resource Identification Initiative To cite this cell line use: ZR75T (RRID:CVCL_IW49)
Comments Part of: MD Anderson Cell Lines Project.
Population: Caucasian.
Omics: Protein expression by reverse-phase protein arrays.
Sequence variations Mutation; HGNC; 5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0588 (ZR-75-1)
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line
Web pages https://tcpaportal.org/mclp/
Publications

PubMed=8430082; DOI=10.1073/pnas.90.3.1112
Keyomarsi K., Pardee A.B.
Redundant cyclin overexpression and gene amplification in breast cancer cells.
Proc. Natl. Acad. Sci. U.S.A. 90:1112-1116(1993)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Other Wikidata; Q54996136
Entry history
Entry creation03-Mar-2017
Last entry update23-Sep-2021
Version number7