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Cellosaurus SH-N (CVCL_IY17)

[Text version]
Cell line name SH-N
Synonyms SK-N-SH-N
Accession CVCL_IY17
Resource Identification Initiative To cite this cell line use: SH-N (RRID:CVCL_IY17)
Comments Population: Caucasian.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; 427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0531 (SK-N-SH)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line
Publications

PubMed=3026862; DOI=10.1159/000163368
Sidell N., Sarafian T., Kelly M., Tsuchida T., Haussler M.
Retinoic acid-induced differentiation of human neuroblastoma: a cell variant system showing two distinct responses.
Exp. Cell Biol. 54:287-300(1986)

Cross-references
Cell line databases/resources cancercelllines; CVCL_IY17
Encyclopedic resources Wikidata; Q54953222
Entry history
Entry creation15-May-2017
Last entry update05-Oct-2023
Version number12