| Cell line name | MDCK-P-gp |
|---|---|
| Accession | CVCL_IZ19 |
| Resource Identification Initiative | To cite this cell line use: MDCK-P-gp (RRID:CVCL_IZ19) |
| Comments | Characteristics: Developed to assess drugs as substrates for p-glycoprotein (ABCB1/MDR). Expresses high level of ABCB1/MDR1. Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin). Derived from site: In situ; Kidney; UBERON=UBERON_0002113. Cell type: Epithelial cell of kidney; CL=CL_0002518. |
| Species of origin | Canis lupus familiaris (Dog) (Canis familiaris)
(NCBI Taxonomy: 9615)
Breed/subspecies: Cocker Spaniel. |
| Hierarchy | Parent: CVCL_0422 (MDCK) |
| Sex of cell | Female |
| Age at sampling | Adult |
| Category | Spontaneously immortalized cell line |
| Publications | PubMed=28093773; DOI=10.1111/jvp.12390 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54904786 |
| Entry history | |
| Entry creation | 15-May-2017 |
| Last entry update | 05-Oct-2023 |
| Version number | 7 |