ID   MDCK-P-gp
DR   Wikidata; Q54904786
RX   PubMed=28093773;
CC   Characteristics: Developed to assess drugs as substrates for p-glycoprotein (ABCB1/MDR). Expresses high level of ABCB1/MDR1.
CC   Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
CC   Derived from sampling site: Kidney.
CC   Breed/subspecies: Cocker Spaniel.
OX   NCBI_TaxID=9615; ! Canis lupus familiaris
HI   CVCL_0422 ! MDCK
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 15-05-17; Last updated: 19-12-19; Version: 4
RX   PubMed=28093773; DOI=10.1111/jvp.12390;
RA   Mealey K.L., Dassanayake S., Burke N.S.;
RT   "Establishment of a cell line for assessing drugs as canine
RT   P-glycoprotein substrates: proof of principle.";
RL   J. Vet. Pharmacol. Ther. 40:545-551(2017).