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Cellosaurus JR-1 (CVCL_J063)

Cell line name JR-1
Synonyms JR1
Accession CVCL_J063
Resource Identification Initiative To cite this cell line use: JR-1 (RRID:CVCL_J063)
Comments Doubling time: ~29 hours (PubMed=3730258).
Omics: Exosome proteome analysis.
Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A8SL (JR1cmyc5)CVCL_A8SI (JR1neo20)CVCL_A8SJ (JR1Nmyc6)
CVCL_A8SK (JR1Nmyc9)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=3730258; DOI=10.1038/bjc.1986.155
Clayton J.P., Pincott J.R., van den Berghe J.A., Kemshead J.T.
Comparative studies between a new human rhabdomyosarcoma cell line, JR-1 and its tumour of origin.
Br. J. Cancer 54:83-90(1986)

CLPUB00569
Dickman P.S., Tsokos M.G., Triche T.J.
Biology of rhabdomyosarcoma: cell culture, xenografts, and animal models.
(In) Rhabdomyosarcoma and related tumors in children and adolescents; Maurer H.M., Ruymann F.B., Pochedly C.E. (eds.); pp.49-88; CRC Press; Boca Raton (1991)

PubMed=23882450; DOI=10.3389/fonc.2013.00183
Hinson A.R.P., Jones R., Crose L.E.S., Belyea B.C., Barr F.G., Linardic C.M.
Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research: utility and pitfalls.
Front. Oncol. 3:183.1-183.12(2013)

PubMed=31448612; DOI=10.1021/acs.jproteome.9b00157
Rammal G., Fahs A., Kobeissy F., Mechref Y., Zhao J.-F., Zhu R., Diab-Assaf M., Saab R., Ghayad S.E.
Proteomic profiling of rhabdomyosarcoma-derived exosomes yield insights into their functional role in paracrine signaling.
J. Proteome Res. 18:3567-3579(2019)

Cross-references
Encyclopedic resources Wikidata; Q54899056
Polymorphism and mutation databases Cosmic; 687952
Proteomic databases PRIDE; PXD007755
Entry history
Entry creation11-Feb-2013
Last entry update29-Jun-2023
Version number15