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Cellosaurus SK-MEL-28-Luc (CVCL_J267)

[Text version]
Cell line name SK-MEL-28-Luc
Accession CVCL_J267
Resource Identification Initiative To cite this cell line use: SK-MEL-28-Luc (RRID:CVCL_J267)
Comments Population: Caucasian.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Melanocyte of skin; CL=CL_1000458.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 1773; CDK4; Simple; p.Arg24Cys (c.70C>T); ClinVar=VCV000016928; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 3236; EGFR; Simple; p.Pro753Ser (c.2257C>T); ClinVar=VCV000376081; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Thr167Ala (c.499A>G); ClinVar=VCV001686107; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.-57A>C (c.161A>C) (A161C); ClinVar=VCV000242210; Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Leu145Arg (c.434T>G); ClinVar=VCV001027110; Zygosity=Homozygous (from parent cell line).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0526 (SK-MEL-28)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX,Y
CSF1PO10
D5S81813
D7S8209.3,10
D13S31711,12
D16S5399,12
TH017
TPOX8,12
vWA19

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Cross-references
Cell line collections (Providers) JCRB; JCRB1376
JCRB; NIHS0641 - Discontinued
Cell line databases/resources cancercelllines; CVCL_J267
Encyclopedic resources Wikidata; Q54954015
Entry history
Entry creation11-Feb-2013
Last entry update05-Oct-2023
Version number22