Home  |  Contact

Cellosaurus NtG20.i7 (CVCL_JA65)

[Text version]

Cell line name NtG20.i7
Accession CVCL_JA65
Resource Identification Initiative To cite this cell line use: NtG20.i7 (RRID:CVCL_JA65)
Comments Characteristics: Supports HBV replication for up to 35 days with production of infectious HBV in the culture supernatant.
Knockout cell: Method=shRNA knockdown; HGNC; 29233; MAVS.
Transfected with: HGNC; 10905; SLC10A1.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Sequence variations NRAS p.Gln61Leu (c.182A>T) (ClinVar=VCV000375874) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line

PubMed=28338936; DOI=10.1093/intimm/dxx012
Yao W.-L., Ikeda S., Tsukamoto Y., Shindo K., Otakaki Y., Qin M., Iwasawa Y., Takeuchi F., Kaname Y., Chou Y.-C., Chang C., Watashi K., Wakita T., Noda T., Kato H., Fujita T.
Establishment of a human hepatocellular cell line capable of maintaining long-term replication of hepatitis B virus.
Int. Immunol. 29:109-120(2017)

Other Wikidata; Q54931114
Entry history
Entry creation15-May-2017
Last entry update02-Jul-2020
Version number8