ID   HEp-3
AC   CVCL_JB77
SY   H.Ep. #3; H.Ep. No. 3; HEp3; Human Epidermoid carcinoma #3
DR   BTO; BTO:0005139
DR   Wikidata; Q54882764
RX   DOI=10.1007/978-1-4757-1647-4_13;
RX   PubMed=1327511;
RX   PubMed=3119604;
RX   PubMed=5835037;
RX   PubMed=9650562;
RX   PubMed=13209540;
RX   PubMed=13261081;
CC   Population: African American.
CC   Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
DI   NCIt; C4040; Buccal mucosa squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   62Y
CA   Cancer cell line
DT   Created: 15-05-17; Last updated: 29-06-23; Version: 8
//
RX   DOI=10.1007/978-1-4757-1647-4_13;
RA   Biedler J.L.;
RT   "Chromosome abnormalities in human tumor cells in culture.";
RL   (In) Human tumor cells in vitro; Fogh J. (eds.); pp.359-394; Springer; New York (1975).
//
RX   PubMed=1327511;
RA   Testa J.E.;
RT   "Loss of the metastatic phenotype by a human epidermoid carcinoma cell
RT   line, HEp-3, is accompanied by increased expression of tissue
RT   inhibitor of metalloproteinase 2.";
RL   Cancer Res. 52:5597-5603(1992).
//
RX   PubMed=3119604; DOI=10.1002/jcp.1041330212;
RA   Ossowski L., Russo H., Gartner M.F.R.M., Wilson E.L.;
RT   "Growth of a human carcinoma (HEp3) in nude mice: rapid and efficient
RT   metastasis.";
RL   J. Cell. Physiol. 133:288-296(1987).
//
RX   PubMed=5835037; DOI=10.1093/jnci/35.3.435;
RA   Miles C.P., O'Neill F.;
RT   "Chromosomes of some heterotransplanted human tumors. II. H.Ep. no. 1,
RT   H.Ep. no. 3, and H.Ep. no. 5.";
RL   J. Natl. Cancer Inst. 35:435-458(1965).
//
RX   PubMed=9650562; DOI=10.1002/(SICI)1097-0215(19980717)77:2<257::AID-IJC15>3.0.CO;2-8;
RA   Lyu M.-A., Choi Y.-K., Park B.-N., Kim B.-J., Park I.-K., Hyun B.-H.,
RA   Kook Y.-H.;
RT   "Over-expression of urokinase receptor in human epidermoid-carcinoma
RT   cell line (HEp3) increases tumorigenicity on chorio-allantoic membrane
RT   and in severe-combined-immunodeficient mice.";
RL   Int. J. Cancer 77:257-263(1998).
//
RX   PubMed=13209540;
RA   Toolan H.W.;
RT   "Transplantable human neoplasms maintained in cortisone-treated
RT   laboratory animals: H.S. No. 1; H.Ep. No. 1; H.Ep. No. 2; H.Ep. No. 3;
RT   and H.Emb.Rh. No. 1.";
RL   Cancer Res. 14:660-666(1954).
//
RX   PubMed=13261081;
RA   Moore A.E., Sabachewsky L., Toolan H.W.;
RT   "Culture characteristics of four permanent lines of human cancer
RT   cells.";
RL   Cancer Res. 15:598-602(1955).
//