Home  |  Contact

Cellosaurus H/Rb-CL2 (CVCL_JE91)

Cell line name H/Rb-CL2
Synonyms H/RB-CL2
Accession CVCL_JE91
Resource Identification Initiative To cite this cell line use: H/Rb-CL2 (RRID:CVCL_JE91)
Comments Characteristics: Corrects the lack of expression of RB1 in the parent cell line which is due to an homozygous mutation p.Tyr325Ter (c.975T>A).
Transfected with: HGNC; 9884; RB1.
Sequence variations Heterozygous for MAPK1 p.Arg79Lys (c.236G>A) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
TP53 p.Arg280Thr (c.839G>C) (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0126 (5637)
Sex of cell Male
Age at sampling 68Y
Category Cancer cell line

Takahashi R., Benedict W.F.
Rb transferred cells and method.
Patent number WO1992022640A1, 23-Dec-1992

Cell line collections ATCC; CRL-10708 - Discontinued
Cell line databases/resources CCRID; 3142C0001000000498
Other Wikidata; Q54871901