Cellosaurus A-375 NRAS p.Q61K (CVCL_JF22)

Cell line name A-375 NRAS p.Q61K
Synonyms NRAS mutant-A375 Isogenic Cell Line
Accession CVCL_JF22
Resource Identification Initiative To cite this cell line use: A-375 NRAS p.Q61K (RRID:CVCL_JF22)
Comments Characteristics: Resistant to BRAF inhibitor drugs.
Sequence variation: Homozygous for NRAS p.Gln61Lys; by CRISPR/Cas9 (ATCC).
Sequence variation: Homozygous for BRAF p.Val600Glu (from parent cell line).
Disease Amelanotic melanoma (NCIt: C3802)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0132 (A-375)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO11,12
D13S31711,14
D16S5399
D5S81812
D7S8209
TH018
TPOX8,10
vWA16,17
Cross-references
Cell line collections ATCC; CRL-1619IG-2