Cellosaurus cell line ED-40515 (CVCL_JF68)

PubMed=2866223; DOI=10.1084/jem.162.6.2169
Maeda M., Shimizu A., Ikuta K., Okamoto H., Kashihara M., Uchiyama T., Honjo T., Yodoi J.
Origin of human T-lymphotrophic virus I-positive T cell lines in adult T cell leukemia. Analysis of T cell receptor gene rearrangement.
J. Exp. Med. 162:2169-2174(1985)

PubMed=7662981; DOI=10.1182/blood.V86.6.2350.bloodjournal8662350
Imada K., Takaori-Kondo A., Akagi T., Shimotohno K., Sugamura K., Hattori T., Yamabe H., Okuma M., Uchiyama T.
Tumorigenicity of human T-cell leukemia virus type I-infected cell lines in severe combined immunodeficient mice and characterization of the cells proliferating in vivo.
Blood 86:2350-2357(1995)

PubMed=15638850; DOI=10.1111/j.1365-2141.2004.05255.x
Ueda M., Imada K., Imura A., Koga H., Hishizawa M., Uchiyama T.
Expression of functional interleukin-21 receptor on adult T-cell leukaemia cells.
Br. J. Haematol. 128:169-176(2005)

PubMed=16314839; DOI=10.1038/sj.onc.1209256
Ahsan M.K., Masutani H., Yamaguchi Y., Kim Y.-C., Nosaka K., Matsuoka M., Nishinaka Y., Maeda M., Yodoi J.
Loss of interleukin-2-dependency in HTLV-I-infected T cells on gene silencing of thioredoxin-binding protein-2.
Oncogene 25:2181-2191(2006)

PubMed=32210945; DOI=10.3389/fmicb.2020.00356
Maeda M., Tanabe-Shibuya J., Miyazato P., Masutani H., Yasunaga J.-i., Usami K., Shimizu A., Matsuoka M.
IL-2/IL-2 receptor pathway plays a crucial role in the growth and malignant transformation of HTLV-1-infected T cells to develop adult T-cell leukemia.
Front. Microbiol. 11:356.1-356.17(2020)

PubMed=34794206; DOI=10.1111/cas.15204
Ikebe E., Shimosaki S., Hasegawa H., Iha H., Tsukamoto Y., Wang Y., Sasaki D., Imaizumi Y., Miyazaki Y., Yanagihara K., Hamaguchi I., Morishita K.
TAS-116 (pimitespib), a heat shock protein 90 inhibitor, shows efficacy in preclinical models of adult T-cell leukemia.
Cancer Sci. 113:684-696(2022)