Cellosaurus logo
expasy logo

Cellosaurus HepaRG CYP3A4G/7R clone 3 (CVCL_JJ68)

[Text version]
Cell line name HepaRG CYP3A4G/7R clone 3
Synonyms HepaRG C3; C3
Accession CVCL_JJ68
Resource Identification Initiative To cite this cell line use: HepaRG CYP3A4G/7R clone 3 (RRID:CVCL_JJ68)
Comments Characteristics: Transfected with a dual reporter that express RFP under the transcriptional regulation of CYP3A7 in the hepatoblast-like cell state and EGFP under the transcriptional regulation of CYP3A4.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transfected with: UniProtKB; Q9U6Y8; Discosoma sp. red fluorescent protein drFP583 (DsRed, RFP).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatitis C infection (NCIt: C3098)
Hepatocellular carcinoma (NCIt: C3099)
Hepatocellular carcinoma (ORDO: Orphanet_88673)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9720 (HepaRG)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=25101946; DOI=10.1371/journal.pone.0104123
Tsuji S., Kawamura F., Kubiura M., Hayashi A., Ohbayashi T., Kazuki Y., Chesne C., Oshimura M., Tada M.
Dual-color fluorescence imaging to monitor CYP3A4 and CYP3A7 expression in human hepatic carcinoma HepG2 and HepaRG cells.
PLoS ONE 9:E104123-E104123(2014)

Cross-references
Encyclopedic resources Wikidata; Q54882835
Entry history
Entry creation22-Aug-2017
Last entry update05-Oct-2023
Version number8