Home  |  Contact

Cellosaurus Ben-Men-1-LucB (CVCL_JK01)

[Text version]
Cell line name Ben-Men-1-LucB
Accession CVCL_JK01
Resource Identification Initiative To cite this cell line use: Ben-Men-1-LucB (RRID:CVCL_JK01)
Comments Transfected with: HGNC; 11730; TERT.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Brain, falx cerebri; UBERON=UBERON_0006059.
Sequence variations
  • Mutation; HGNC; 7773; NF2; Simple; p.Leu214fs*6 (c.640delC); Zygosity=Hemizygous (PubMed=23151902).
Disease Meningothelial meningioma (NCIt: C4329)
Meningioma (ORDO: Orphanet_2495)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1959 (Ben-Men-1)
Sex of cell Female
Age at sampling 68Y
Category Telomerase immortalized cell line
Publications

PubMed=23151902; DOI=10.1158/0008-5472.CAN-12-1888
Burns S.S., Akhmametyeva E.M., Oblinger J.L., Bush M.L., Huang J., Senner V., Chen C.-S., Jacob A., Welling D.B., Chang L.-S.
Histone deacetylase inhibitor AR-42 differentially affects cell-cycle transit in meningeal and meningioma cells, potently inhibiting NF2-deficient meningioma growth.
Cancer Res. 73:792-803(2013)

PubMed=25596744; DOI=10.18632/oncotarget.2810
Chow H.-Y., Dong B., Duron S.G., Campbell D.A., Ong C.C., Hoeflich K.P., Chang L.-S., Welling D.B., Yang Z.-J., Chernoff J.
Group I Paks as therapeutic targets in NF2-deficient meningioma.
Oncotarget 6:1981-1994(2015)

Cross-references
Encyclopedic resources Wikidata; Q54796000
Entry history
Entry creation15-May-2017
Last entry update05-Oct-2023
Version number10