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Cellosaurus SC4 [Mouse schwannoma] (CVCL_JK03)

[Text version]
Cell line name SC4 [Mouse schwannoma]
Accession CVCL_JK03
Resource Identification Initiative To cite this cell line use: SC4 [Mouse schwannoma] (RRID:CVCL_JK03)
Comments Knockout cell: Method=KO mouse; MGI; MGI:97307; Nf2 (Note=Conditional KO).
Derived from site: In situ; Peripheral nervous system, nerve; UBERON=UBERON_0001021.
Cell type: Schwann cell; CL=CL_0002573.
Disease Mouse schwannoma (NCIt: C21997)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Category Cancer cell line
Publications

PubMed=17234759; DOI=10.1158/0008-5472.CAN-06-1608
Morrison H., Sperka T., Manent J., Giovannini M., Ponta H., Herrlich P.
Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac.
Cancer Res. 67:520-527(2007)

PubMed=28469964
Guo J.-M., Grovola M.R., Xie H., Coggins G.E., Duggan P., Hasan R., Huang J.-L., Lin D.W., Song C., Witek G.M., Berritt S., Schultz D.C., Field J.
Comprehensive pharmacological profiling of neurofibromatosis cell lines.
Am. J. Cancer Res. 7:923-934(2017)

Cross-references
Encyclopedic resources Wikidata; Q54952286
Entry history
Entry creation15-May-2017
Last entry update30-Jan-2024
Version number6