| Cell line name | MCF7T1 |
|---|---|
| Accession | CVCL_JX64 |
| Resource Identification Initiative | To cite this cell line use: MCF7T1 (RRID:CVCL_JX64) |
| Comments | Part of: MD Anderson Cell Lines Project. Characteristics: Transfected with reverse tetracycline-controlled transactivator (rtTA), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16. Transfected with: HGNC; 1589; CCNE1 (M-1--L-39 del, M-40 called 'truncation 1'). Transfected with: UniProtKB; P04483; E.coli Tn10 tetR. Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with del 1-360). Omics: Protein expression by reverse-phase protein arrays. |
| Sequence variations | Homozygous for CDKN2A deletion (from parent cell line).Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line). |
| Disease | Invasive ductal carcinoma, not otherwise specified (NCIt: C4194) Derived from metastatic site: Pleural effusion. |
| Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
|
| Hierarchy | Parent: CVCL_V332 (MCF7 Tet-On) |
| Sex of cell | Female |
| Age at sampling | 69Y |
| Category | Cancer cell line |
| Web pages | http://tcpaportal.org/mclp/ |
| Publications | PubMed=21695458; DOI=10.1007/s10549-011-1638-4 PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005 |
| Cross-references | |
| Other | Wikidata; Q54904476 |
| Entry history | |
| Entry creation | 22-Aug-2017 |
| Last entry update | 02-Jul-2020 |
| Version number | 5 |