Cell line name | MCF7T2 |
---|---|
Accession | CVCL_JX65 |
Resource Identification Initiative | To cite this cell line use: MCF7T2 (RRID:CVCL_JX65) |
Comments | Part of: MD Anderson Cell Lines Project. Population: Caucasian. Characteristics: Transfected with reverse tetracycline-controlled transactivator (rtTA), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16. Transfected with: HGNC; 1589; CCNE1 (M-1--N-64 del, M-65 called 'truncation 2'). Transfected with: UniProtKB; P04483; E.coli Tn10 tetR. Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with del 1-360). Omics: Protein expression by reverse-phase protein arrays. |
Sequence variations | Gene deletion; CDKN2A; Zygosity=Homozygous (from parent cell line).Heterozygous for GATA3 p.Asp336Glyfs*17 (c.1006dupG) (from parent cell line).Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line). |
Disease | Invasive ductal carcinoma, not otherwise specified (NCIt: C4194) Derived from metastatic site: Pleural effusion. |
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
|
Hierarchy | Parent: CVCL_V332 (MCF7 Tet-On) |
Sex of cell | Female |
Age at sampling | 69Y |
Category | Cancer cell line |
Web pages | http://tcpaportal.org/mclp/ |
Publications | PubMed=21695458; DOI=10.1007/s10549-011-1638-4 PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005 |
Cross-references | |
Other | Wikidata; Q54904477 |
Entry history | |
Entry creation | 22-Aug-2017 |
Last entry update | 12-Jan-2021 |
Version number | 7 |