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Cellosaurus K562-AVB3 (CVCL_JX91)

[Text version]

Cell line name K562-AVB3
Synonyms K562-avb3; K562 aVb3; K562-alphaVbeta3; avb3-K562; alphaVbeta3-K562
Accession CVCL_JX91
Resource Identification Initiative To cite this cell line use: K562-AVB3 (RRID:CVCL_JX91)
Comments Transfected with: HGNC; 6150; ITGAV.
Transfected with: HGNC; 6156; ITGB3.
Derived from sampling site: Pleural effusion.
Sequence variations BCR-ABL1 gene fusion (from parent cell line).
Homozygous for TP53 p.Gln136fs*13 (c.406_407insC) (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line

PubMed=7525603; DOI=10.1083/jcb.127.4.1129
Blystone S.D., Graham I.L., Lindberg F.P., Brown E.J.
Integrin alpha v beta 3 differentially regulates adhesive and phagocytic functions of the fibronectin receptor alpha 5 beta 1.
J. Cell Biol. 127:1129-1137(1994)

Other Wikidata; Q54899379
Entry history
Entry creation22-Aug-2017
Last entry update12-Mar-2020
Version number6