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Cellosaurus LAP1 (CVCL_JY58)

[Text version]
Cell line name LAP1
Synonyms LAP-1
Accession CVCL_JY58
Resource Identification Initiative To cite this cell line use: LAP1 (RRID:CVCL_JY58)
Comments Characteristics: Has a complete defect in Na+/H+ antiporter activity.
Selected for resistance to: ChEBI; CHEBI:472552; 5-bromo-2'-deoxyuridine (Bromodeoxyuridine; BrdU; BUdR).
Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Connective tissue; UBERON=UBERON_0002384.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/An.
Hierarchy Parent: CVCL_4536 (L-M(TK-))
Sex of cell Male
Age at sampling 100D
Category Spontaneously immortalized cell line
Publications

PubMed=3025840; DOI=10.1073/pnas.83.24.9388
Franchi A., Perucca-Lostanlen D., Pouyssegur J.
Functional expression of a human Na+/H+ antiporter gene transfected into antiporter-deficient mouse L cells.
Proc. Natl. Acad. Sci. U.S.A. 83:9388-9392(1986)

PubMed=2536298; DOI=10.1016/0092-8674(89)90901-X
Sardet C., Franchi A., Pouyssegur J.
Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter.
Cell 56:271-280(1989)

Cross-references
Encyclopedic resources Wikidata; Q54901923
Entry history
Entry creation22-Aug-2017
Last entry update29-Jun-2023
Version number6