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Cellosaurus H357-V3 (CVCL_JY67)

[Text version]
Cell line name H357-V3
Synonyms V3
Accession CVCL_JY67
Resource Identification Initiative To cite this cell line use: H357-V3 (RRID:CVCL_JY67)
Comments Transfected with: HGNC; 6150; ITGAV.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; HGNC; 5173; HRAS; Simple; p.Gly13Ser (c.37G>A); ClinVar=VCV000376323; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Homozygous (from parent cell line).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2462 (H357)
Children:
CVCL_JY68 (H357-VB6)
Sex of cell Male
Age at sampling 74Y
Category Cancer cell line
Publications

PubMed=8552382
Jones J., Sugiyama M., Speight P.M., Watt F.M.
Restoration of alpha V beta 5 integrin expression in neoplastic keratinocytes results in increased capacity for terminal differentiation and suppression of anchorage-independent growth.
Oncogene 12:119-126(1996)

PubMed=11442751; DOI=10.1046/j.0022-202x.2001.01379.x
Thomas G.J., Lewis M.P., Whawell S.A., Russell A., Sheppard D., Hart I.R., Speight P.M., Marshall J.F.
Expression of the alphavbeta6 integrin promotes migration and invasion in squamous carcinoma cells.
J. Invest. Dermatol. 117:67-73(2001)

Cross-references
Encyclopedic resources Wikidata; Q54992480
Entry history
Entry creation22-Aug-2017
Last entry update29-Jun-2023
Version number10