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Cellosaurus H357-VB6 (CVCL_JY68)

[Text version]
Cell line name H357-VB6
Synonyms VB6
Accession CVCL_JY68
Resource Identification Initiative To cite this cell line use: H357-VB6 (RRID:CVCL_JY68)
Comments Transfected with: HGNC; 6150; ITGAV.
Transfected with: HGNC; 6161; ITGB6.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; HGNC; 5173; HRAS; Simple; p.Gly13Ser (c.37G>A); ClinVar=VCV000376323; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Homozygous (from parent cell line).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_JY67 (H357-V3)
Sex of cell Male
Age at sampling 74Y
Category Cancer cell line
Publications

PubMed=11340566; DOI=10.1002/1097-0215(20010601)92:5<641::AID-IJC1243>3.0.CO;2-P
Thomas G.J., Lewis M.P., Hart I.R., Marshall J.F., Speight P.M.
AlphaVbeta6 integrin promotes invasion of squamous carcinoma cells through up-regulation of matrix metalloproteinase-9.
Int. J. Cancer 92:641-650(2001)

PubMed=11442751; DOI=10.1046/j.0022-202x.2001.01379.x
Thomas G.J., Lewis M.P., Whawell S.A., Russell A., Sheppard D., Hart I.R., Speight P.M., Marshall J.F.
Expression of the alphavbeta6 integrin promotes migration and invasion in squamous carcinoma cells.
J. Invest. Dermatol. 117:67-73(2001)

Cross-references
Encyclopedic resources Wikidata; Q54992947
Entry history
Entry creation22-Aug-2017
Last entry update29-Jun-2023
Version number10