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Cellosaurus 409B2 (CVCL_K092)

[Text version]

Cell line name 409B2
Synonyms 409-B2; 409B-2
Accession CVCL_K092
Resource Identification Initiative To cite this cell line use: 409B2 (RRID:CVCL_K092)
Comments From: Center for iPS Cell Research and Application, Kyoto University; Kyoto; Japan.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_DP59 (HDF1388)
Sex of cell Female
Age at sampling 36Y
Category Induced pluripotent stem cell
STR profile Source(s): PubMed=21460823

Markers:
AmelogeninX
CSF1PO11
D3S135816,18
D5S81812
D7S8209,10
D8S11798,10
D13S3179,13
D16S53911,13
D18S5115
D21S1129
FGA20,22
Penta D9,11
Penta E7,19
TH016
TPOX8,9
vWA15,18

Run an STR similarity search on this cell line
Publications

PubMed=21460823; DOI=10.1038/nmeth.1591
Okita K., Matsumura Y., Sato Y., Okada A., Morizane A., Okamoto S., Hong H., Nakagawa M., Tanabe K., Tezuka K., Shibata T., Kunisada T., Takahashi M., Takahashi J., Saji H., Yamanaka S.
A more efficient method to generate integration-free human iPS cells.
Nat. Methods 8:409-412(2011)

PubMed=22802639; DOI=10.1073/pnas.1209979109
Kajiwara M., Aoi T., Okita K., Takahashi R., Inoue H., Takayama N., Endo H., Eto K., Toguchida J., Uemoto S., Yamanaka S.
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells.
Proc. Natl. Acad. Sci. U.S.A. 109:12538-12543(2012)

PubMed=23434393; DOI=10.1016/j.stem.2013.01.009
Kondo T., Asai M., Tsukita K., Kutoku Y., Ohsawa Y., Sunada Y., Imamura K., Egawa N., Yahata N., Okita K., Takahashi K., Asaka I., Aoi T., Watanabe A., Watanabe K., Kadoya C., Nakano R., Watanabe D., Maruyama K., Hori O., Hibino S., Choshi T., Nakahata T., Hioki H., Kaneko T., Naitoh M., Yoshikawa K., Yamawaki S., Suzuki S., Hata R., Ueno S.-I., Seki T., Kobayashi K., Toda T., Murakami K., Irie K., Klein W.L., Mori H., Asada T., Takahashi R., Iwata N., Yamanaka S., Inoue H.
Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Abeta and differential drug responsiveness.
Cell Stem Cell 12:487-496(2013)

PubMed=24259714; DOI=10.1073/pnas.1319061110
Koyanagi-Aoi M., Ohnuki M., Takahashi K., Okita K., Noma H., Sawamura Y., Teramoto I., Narita M., Sato Y., Ichisaka T., Amano N., Watanabe A., Morizane A., Yamada Y., Sato T., Takahashi J., Yamanaka S.
Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells.
Proc. Natl. Acad. Sci. U.S.A. 110:20569-20574(2013)

PubMed=25231866; DOI=10.1038/nature13775
Yamashita A., Morioka M., Kishi H., Kimura T., Yahara Y., Okada M., Fujita K., Sawai H., Ikegawa S., Tsumaki N.
Statin treatment rescues FGFR3 skeletal dysplasia phenotypes.
Nature 513:507-511(2014)

PubMed=25665923; DOI=10.1016/j.scr.2015.01.007
Toyoda T., Mae S.-I., Tanaka H., Kondo Y., Funato M., Hosokawa Y., Sudo T., Kawaguchi Y., Osafune K.
Cell aggregation optimizes the differentiation of human ESCs and iPSCs into pancreatic bud-like progenitor cells.
Stem Cell Res. 14:185-197(2015)

PubMed=26997647; DOI=10.1016/j.stemcr.2016.02.011
Ichiyanagi N., Fujimori K., Yano M., Ishihara-Fujisaki C., Sone T., Akiyama T., Okada Y., Akamatsu W., Matsumoto T., Ishikawa M., Nishimoto Y., Ishihara Y., Sakuma T., Yamamoto T., Tsuiji H., Suzuki N., Warita H., Aoki M., Okano H.
Establishment of in Vitro FUS-associated familial amyotrophic lateral sclerosis model using human induced pluripotent stem cells.
Stem Cell Reports 6:496-510(2016)

PubMed=27476965; DOI=10.1016/j.stem.2016.06.019
Nishizawa M., Chonabayashi K., Nomura M., Tanaka A., Nakamura M., Inagaki A., Nishikawa M., Takei I., Oishi A., Tanabe K., Ohnuki M., Yokota H., Koyanagi-Aoi M., Okita K., Watanabe A., Takaori-Kondo A., Yamanaka S., Yoshida Y.
Epigenetic variation between human induced pluripotent stem cell lines is an indicator of differentiation capacity.
Cell Stem Cell 19:341-354(2016)

Cross-references
Cell line collections RCB; HPS0076
Cell line databases/resources SKIP; SKIP000218
Gene expression databases GEO; GSM1040275
GEO; GSM1040345
GEO; GSM1489195
GEO; GSM1489224
GEO; GSM1489251
GEO; GSM1489428
Other Wikidata; Q54602867
Entry history
Entry creation11-Feb-2013
Last entry updated25-Feb-2019
Version number7