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Cellosaurus RPTEC/TERT1 (CVCL_K278)

[Text version]

Cell line name RPTEC/TERT1
Synonyms RPTEC TERT1; RPTEC/TERT 1; Renal Proximal Tubule Epithelial Cells/TERT-immortalized 1
Accession CVCL_K278
Resource Identification Initiative To cite this cell line use: RPTEC/TERT1 (RRID:CVCL_K278)
Comments Doubling time: ~96 hours (PubMed=18715936); 76.8 hours (PubMed=31078587).
Transfected with: HGNC; 11730; TERT.
Omics: Metabolome analysis.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_WN16 (HREC24T)CVCL_WN15 (HRTPT)CVCL_RM67 (RPTEC/TERT1 OAT1)
CVCL_VR68 (RPTEC/TERT1 OAT3)CVCL_RM66 (RPTEC/TERT1 OCT2)
Sex of cell Male
Age at sampling Adult
Category Telomerase immortalized cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX,Y
CSF1PO11
D5S8189,11
D7S82010
D13S31711,13
D16S53911,12
TH019,9.3
TPOX8,11
vWA16,18

Run an STR similarity search on this cell line
Web pages http://www.evercyte.com/rptec-tert-1.html
http://www.proteinatlas.org/learn/cellines
Publications

PubMed=18715936; DOI=10.1152/ajprenal.90405.2008
Wieser M., Stadler G., Jennings P., Streubel B., Pfaller W., Ambros P.F., Riedl C., Katinger H., Grillari J., Grillari-Voglauer R.
hTERT alone immortalizes epithelial cells of renal proximal tubules without changing their functional characteristics.
Am. J. Physiol. Renal Physiol. 295:F1365-F1375(2008)

PubMed=21103459; DOI=10.1039/c0mb00146e
Ellis J.K., Athersuch T.J., Cavill R., Radford R., Slattery C., Jennings P., McMorrow T., Ryan M.P., Ebbels T.M., Keun H.C.
Metabolic response to low-level toxicant exposure in a novel renal tubule epithelial cell system.
Mol. Biosyst. 7:247-257(2011)

PubMed=25536518; DOI=10.1016/j.tiv.2014.11.015
Crean D., Bellwon P., Aschauer L., Limonciel A., Moenks K., Hewitt P.G., Schmidt T., Herrgen K., Dekant W., Lukas A., Bois F., Wilmes A., Jennings P., Leonard M.O.
Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing.
Toxicol. In Vitro 30:128-137(2015)

PubMed=31078587; DOI=10.1016/j.taap.2019.05.007
Shrestha S., Garrett S.H., Sens D.A., Zhou X.-D., Guyer R., Somji S.
Characterization and determination of cadmium resistance of CD133(+)/CD24(+) and CD133(-)/CD24(+) cells isolated from the immortalized human proximal tubule cell line, RPTEC/TERT1.
Toxicol. Appl. Pharmacol. 375:5-16(2019)

Cross-references
Cell line collections ATCC; CRL-4031
Biological sample resources BioSample; SAMN03471734
Metabolomic databases MetaboLights; MTBLS9
Other Wikidata; Q54951284
Entry history
Entry creation11-Feb-2013
Last entry updated24-May-2019
Version number10