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Cellosaurus sNF02.2 (CVCL_K280)

[Text version]
Cell line name sNF02.2
Synonyms sNF02-2
Accession CVCL_K280
Resource Identification Initiative To cite this cell line use: sNF02.2 (RRID:CVCL_K280)
Comments Doubling time: ~26 hours (ATCC=CRL-2885).
Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
Disease Malignant peripheral nerve sheath tumor (NCIt: C3798)
Neurofibromatosis type 1 (NCIt: C3273)
Malignant peripheral nerve sheath tumor (ORDO: Orphanet_3148)
Neurofibromatosis type 1 (ORDO: Orphanet_636)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81812
D7S82010,11
D13S31711,14
D16S53911,12
TH017,9
TPOX8,12
vWA16

Run an STR similarity search on this cell line
Web pages http://technologylicensing.research.ufl.edu/technologies/11276_human-schwann-cell-like-cell-line-snf02-2
Publications

PubMed=14762442; DOI=10.1038/sj.onc.1207068
Li Y.-W., Rao P.K., Wen R., Song Y., Muir D.F. IV, Wallace P., van Horne S.J., Tennekoon G.I., Kadesch T.
Notch and Schwann cell transformation.
Oncogene 23:1146-1152(2004)

PubMed=22346343; DOI=10.4137/TOG.S8830
Sun D., Tainsky M.A., Haddad R.
Oncogene mutation survey in MPNST cell lines enhances the dominant role of hyperactive Ras in NF1 associated pro-survival and malignancy.
Transl. Oncogenomics 5:1-7(2012)

PubMed=28469964
Guo J.-M., Grovola M.R., Xie H., Coggins G.E., Duggan P., Hasan R., Huang J.-L., Lin D.W., Song C., Witek G.M., Berritt S., Schultz D.C., Field J.
Comprehensive pharmacological profiling of neurofibromatosis cell lines.
Am. J. Cancer Res. 7:923-934(2017)

PubMed=32642732; DOI=10.1093/noajnl/vdz049
Pemov A., Li H., Presley W., Wallace M.R., Miller D.T.
Genetics of human malignant peripheral nerve sheath tumors.
Neurooncol. Adv. 2:I50-I61(2020)

Cross-references
Cell line collections (Providers) ATCC; CRL-2885
Biological sample resources BioSample; SAMN03471811
Encyclopedic resources Wikidata; Q54955056
Polymorphism and mutation databases Cosmic; 1644554
Entry history
Entry creation11-Feb-2013
Last entry update29-Jun-2023
Version number17