Cellosaurus CellSensor LEF/TCF-bla SW480 (CVCL_KS03)

Cell line name CellSensor LEF/TCF-bla SW480
Synonyms LEF/TCF-bla SW480; LEF/TCF-bla SW 480
Accession CVCL_KS03
Resource Identification Initiative To cite this cell line use: CellSensor LEF/TCF-bla SW480 (RRID:CVCL_KS03)
Comments Characteristics: Transfected with a plasmid containing a beta-lactamase reporter gene under control of beta-catenin/LEF/TCF binding elements.
Transfected with: UniProtKB; P62593; E.coli beta-lactamase bla (with p.Met1_Phe22del, p.Ala23Met, p.Val82Ile and p.Met184Val).
Sequence variation Homozygous for APC p.Gln1338Ter (from parent cell line).
Homozygous for KRAS p.Gly12Val (from parent cell line).
Heterozygous for TP53 p.Arg273His and p.Pro309Ser (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0546 (SW480)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
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