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Cellosaurus CellSensor LEF/TCF-bla SW480 (CVCL_KS03)

[Text version]

Cell line name CellSensor LEF/TCF-bla SW480
Synonyms LEF/TCF-bla SW480; LEF/TCF-bla SW 480
Accession CVCL_KS03
Resource Identification Initiative To cite this cell line use: CellSensor LEF/TCF-bla SW480 (RRID:CVCL_KS03)
Comments Characteristics: Transfected with a plasmid containing a beta-lactamase reporter gene under control of beta-catenin/LEF/TCF binding elements.
Transfected with: UniProtKB; P62593; E.coli beta-lactamase bla (with p.Met1_Phe22del, p.Ala23Met, p.Val82Ile and p.Met184Val).
Sequence variations Homozygous for APC p.Gln1338Ter (c.4012C>T) (from parent cell line).
Homozygous for KRAS p.Gly12Val (c.35G>T) (ClinVar=VCV000012583) (from parent cell line).
Heterozygous for TP53 p.Arg273His (c.818G>A) (ClinVar=VCV000012366) and p.Pro309Ser (c.925C>T) (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0546 (SW480)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Web pages https://www.thermofisher.com/order/catalog/product/K1675
Other Wikidata; Q54809199
Entry history
Entry creation22-Aug-2017
Last entry update02-Jul-2020
Version number5