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Cellosaurus HepG2 Tet-On Advanced (CVCL_KT01)

[Text version]

Cell line name HepG2 Tet-On Advanced
Accession CVCL_KT01
Resource Identification Initiative To cite this cell line use: HepG2 Tet-On Advanced (RRID:CVCL_KT01)
Comments Characteristics: Transfected with an advanced reverse tetracycline-controlled transactivator (rtTA2(S)-M2), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16.
Transfected with: UniProtKB; P04483; E.coli Tn10 tetR.
Transfected with: UniProtKB; P04486; Human herpesvirus 1 VP16 (UL28) (with del 1-360).
Sequence variations NRAS p.Gln61Leu (c.182A>T) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Web pages http://www.clontech.com/US/Products/Inducible_Systems/Tetracycline-Inducible_Expression/ibcGetAttachment.jsp?cItemId=26901
Cross-references
Other Wikidata; Q54882848
Entry history
Entry creation22-Aug-2017
Last entry updated05-Jul-2019
Version number5