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Cellosaurus SU-DHL-4/12V (CVCL_KU32)

[Text version]

Cell line name SU-DHL-4/12V
Synonyms DHL-4/12V
Accession CVCL_KU32
Resource Identification Initiative To cite this cell line use: SU-DHL-4/12V (RRID:CVCL_KU32)
Comments Selected for resistance to: ChEBI; CHEBI:28445; Vincristine (VCR).
Derived from sampling site: Peritoneal effusion.
Sequence variations IGH-BCL2 gene fusion (from parent cell line).
Heterozygous for EZH2 p.Tyr646Ser (c.1937A>C) (Y641S) and p.Tyr666Asn (c.1996T>A) (Y661N) (from parent cell line).
Homozygous for TP53 p.Arg273Cys (c.817C>T) (ClinVar=VCV000043594) (from parent cell line).
Disease Diffuse large B-cell lymphoma germinal center B-cell type (NCIt: C36080)
Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0539 (SU-DHL-4)
Sex of cell Male
Age at sampling 38Y
Category Cancer cell line

PubMed=18357372; DOI=10.3892/or.19.4.889
Pop I., Pop L., Vitetta E.S., Ghetie M.-A.
Generation of multidrug resistant lymphoma cell lines stably expressing P-glycoprotein.
Oncol. Rep. 19:889-895(2008)

Other Wikidata; Q54970719
Entry history
Entry creation22-Aug-2017
Last entry update02-Jul-2020
Version number8