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Cellosaurus T-47D Tet-Off (CVCL_KU40)

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Cell line name T-47D Tet-Off
Accession CVCL_KU40
Resource Identification Initiative To cite this cell line use: T-47D Tet-Off (RRID:CVCL_KU40)
Comments Characteristics: Transfected with the tetracycline transactivator (tTA) protein, a fusion of tetR with the activation domain of HSV-1 VP16.
Transfected with: UniProtKB; P04483; E.coli Tn10 tetR.
Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with del 1-360).
Discontinued: Clontech; Catalog number 630924/631145.
Sequence variations Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0553 (T-47D)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Cross-references
Other Wikidata; Q54971345
Entry history
Entry creation22-Aug-2017
Last entry update20-May-2021
Version number7