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Cellosaurus InCELL Hunter A549 PRMT3 Methyltransferase (CVCL_KW00)

[Text version]
Cell line name InCELL Hunter A549 PRMT3 Methyltransferase
Accession CVCL_KW00
Resource Identification Initiative To cite this cell line use: InCELL Hunter A549 PRMT3 Methyltransferase (RRID:CVCL_KW00)
Comments Population: Caucasian.
Characteristics: InCELL Hunter cell lines express a transfected target protein fragment tagged with a beta-galactosidase fragment (enhanced ProLabel=ePL). The technology measures compound binding to an intracellular target by detecting changes in protein stability. The amount of fusion is quantified through the addition of substrate and a second enzyme fragment (Enzyme acceptor=EA).
Transfected with: HGNC; 30163; PRMT3 (with del 1-210).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) DiscoverX; 96-0072C15
Cell line databases/resources cancercelllines; CVCL_KW00
Encyclopedic resources Wikidata; Q54897711
Entry history
Entry creation22-Aug-2017
Last entry update05-Oct-2023
Version number10