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Cellosaurus InCELL Hunter U2OS BCL2-BAX Protein Binding (CVCL_KW11)

[Text version]

Cell line name InCELL Hunter U2OS BCL2-BAX Protein Binding
Synonyms InCELL Hunter U2OS Bcl2-Bax
Accession CVCL_KW11
Resource Identification Initiative To cite this cell line use: InCELL Hunter U2OS BCL2-BAX Protein Binding (RRID:CVCL_KW11)
Comments Characteristics: InCELL Hunter cell lines express a transfected target protein fragment tagged with a beta-galactosidase fragment (enhanced ProLabel=ePL). The technology measures compound binding to an intracellular target by detecting changes in protein stability. The amount of fusion is quantified through the addition of substrate and a second enzyme fragment (Enzyme acceptor=EA).
Transfected with: HGNC; 990; BCL2.
Transfected with: HGNC; 959; BAX (with del 1-51 and 73-192).
Derived from sampling site: Bone; tibia.
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Cross-references
Cell line collections DiscoverX; 96-0010C3
Other Wikidata; Q54897726
Entry history
Entry creation22-Aug-2017
Last entry update12-Mar-2020
Version number4