ID   InCELL Hunter U2OS BCL2-BAX Protein Binding
SY   InCELL Hunter U2OS Bcl2-Bax
DR   DiscoverX; 96-0010C3
DR   Wikidata; Q54897726
CC   Characteristics: InCELL Hunter cell lines express a transfected target protein fragment tagged with a beta-galactosidase fragment (enhanced ProLabel=ePL). The technology measures compound binding to an intracellular target by detecting changes in protein stability. The amount of fusion is quantified through the addition of substrate and a second enzyme fragment (Enzyme acceptor=EA).
CC   Transfected with: HGNC; 990; BCL2.
CC   Transfected with: HGNC; 959; BAX (with del 1-51 and 73-192).
CC   Derived from sampling site: Bone; tibia.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0042 ! U2OS
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 12-03-20; Version: 4