ID   PathHunter HEK 293 EDG1 Total GPCR Internalization
AC   CVCL_KZ45
SY   PathHunter EDG1 Total GPCR Internalization HEK 293
DR   DiscoverX; 93-0784C1
DR   Wikidata; Q54938025
CC   Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
CC   Transfected with: HGNC; 3165; S1PR1.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 22-08-17; Last updated: 29-06-23; Version: 6
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