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Cellosaurus PathHunter HEK 293 GPR120L Total GPCR Internalization (CVCL_KZ51)

Cell line name PathHunter HEK 293 GPR120L Total GPCR Internalization
Synonyms PathHunter GPR120L Total GPCR Internalization HEK 293
Accession CVCL_KZ51
Resource Identification Initiative To cite this cell line use: PathHunter HEK 293 GPR120L Total GPCR Internalization (RRID:CVCL_KZ51)
Comments Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Transfected with: HGNC; 19061; FFAR4 (isoform 1).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Cross-references
Cell line collections (Providers) DiscoverX; 93-0801C1
Encyclopedic resources Wikidata; Q54938032
Entry history
Entry creation22-Aug-2017
Last entry update29-Jun-2023
Version number6