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Cellosaurus PathHunter HEK 293 GRPR beta-arrestin (CVCL_KZ57)

[Text version]

Cell line name PathHunter HEK 293 GRPR beta-arrestin
Accession CVCL_KZ57
Resource Identification Initiative To cite this cell line use: PathHunter HEK 293 GRPR beta-arrestin (RRID:CVCL_KZ57)
Comments Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Transfected with: HGNC; 4609; GRPR.
Transfected with: HGNC; 712; ARRB2.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from sampling site: Fetal kidney.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Cell line collections DiscoverX; 93-0229C1
Other Wikidata; Q54938050
Entry history
Entry creation22-Aug-2017
Last entry update29-Oct-2020
Version number4