ID   SNU-668-DOX
AC   CVCL_L051
SY   SNU-668R-DOX/50
DR   Wikidata; Q54955244
RX   PubMed=14734480;
RX   PubMed=19956504;
CC   Part of: Seoul National University (SNU) cell line collection.
CC   Population: Korean.
CC   Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000177777; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ser215Asn (c.644G>A); ClinVar=VCV000376662; Zygosity=Homozygous (from parent cell line).
CC   Derived from metastatic site: Ascites.
DI   NCIt; C5250; Gastric signet ring cell adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_5081 ! SNU-668
SX   Male
AG   63Y
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 20-05-21; Version: 14
//
RX   PubMed=14734480; DOI=10.1158/1078-0432.CCR-1025-3;
RA   Kang H.-C., Kim I.-J., Park J.-H., Shin Y., Ku J.-L., Jung M.S.,
RA   Yoo B.C., Kim H.K., Park J.-G.;
RT   "Identification of genes with differential expression in acquired
RT   drug-resistant gastric cancer cells using high-density oligonucleotide
RT   microarrays.";
RL   Clin. Cancer Res. 10:272-284(2004).
//
RX   PubMed=19956504; DOI=10.4143/crt.2005.37.1.1;
RA   Ku J.-L., Park J.-G.;
RT   "Biology of SNU cell lines.";
RL   Cancer Res. Treat. 37:1-19(2005).
//