ID   SNU-719-5FU
AC   CVCL_L052
SY   SNU-719R-5-FU/600
DR   Wikidata; Q54955256
RX   PubMed=14734480;
RX   PubMed=19956504;
CC   Part of: Seoul National University (SNU) cell line collection.
CC   Population: Korean.
CC   Selected for resistance to: ChEBI; CHEBI:46345; 5-fluorouracil (5-FU).
CC   Sequence variation: Mutation; HGNC; 2514; CTNNB1; Simple; p.Gly34Val (c.101G>T); ClinVar=VCV000017582; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Pro104Arg (c.311C>G); Zygosity=Heterozygous (from parent cell line).
CC   Derived from sampling site: Stomach.
DI   NCIt; C5473; Gastric tubular adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_5086 ! SNU-719
SX   Male
AG   53Y
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 20-05-21; Version: 12
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RX   PubMed=14734480; DOI=10.1158/1078-0432.CCR-1025-3;
RA   Kang H.-C., Kim I.-J., Park J.-H., Shin Y., Ku J.-L., Jung M.S.,
RA   Yoo B.C., Kim H.K., Park J.-G.;
RT   "Identification of genes with differential expression in acquired
RT   drug-resistant gastric cancer cells using high-density oligonucleotide
RT   microarrays.";
RL   Clin. Cancer Res. 10:272-284(2004).
//
RX   PubMed=19956504; DOI=10.4143/crt.2005.37.1.1;
RA   Ku J.-L., Park J.-G.;
RT   "Biology of SNU cell lines.";
RL   Cancer Res. Treat. 37:1-19(2005).
//