Cellosaurus YD-8 (CVCL_L079)

Cell line name YD-8
Synonyms YD8
Accession CVCL_L079
Resource Identification Initiative To cite this cell line use: YD-8 (RRID:CVCL_L079)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 29.3 hours (PubMed=16264262).
Sequence variation: TP53 p.Arg273His (PubMed=16264262).
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): KCLB; PubMed=16264262

Markers:
AmelogeninX
CSF1PO10
D13S3178,10
D16S5399,11
D18S5115,16
D21S1129,30
D3S135815.2 (KLCB)
15,16 (PubMed=16264262)
D5S81812
D7S82010,13
D8S117913,16
FGA24
Penta D13
Penta E12,15
TH017,9
TPOX8,11
vWA14,17
Publications

PubMed=16264262; DOI=10.1038/emm.2005.48
Lee E.J., Kim J., Lee S.A., Kim E.-J., Chun Y.-C., Ryu M.H., Yook J.-I.
Characterization of newly established oral cancer cell lines derived from six squamous cell carcinoma and two mucoepidermoid carcinoma cells.
Exp. Mol. Med. 37:379-390(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=23708675; DOI=10.3892/ijo.2013.1953
Oh J.-E., Kim J.-O., Shin J.-Y., Zhang X.-H., Won H.-S., Chun S.-H., Jung C.-K., Park W.-S., Nam S.-W., Eun J.-W., Kang J.-H.
Molecular genetic characterization of p53 mutated oropharyngeal squamous cell carcinoma cells transformed with human papillomavirus E6 and E7 oncogenes.
Int. J. Oncol. 43:383-393(2013)

PubMed=28053903; DOI=10.5125/jkaoms.2016.42.6.337
Jo D.-W., Kim Y.-K., Yun P.-Y.
The influence of p53 mutation status on the anti-cancer effect of cisplatin in oral squamous cell carcinoma cell lines.
J. Korean Assoc. Oral Maxillofac. Surg. 42:337-344(2016)

Cross-references
Cell line collections KCLB; 60501
Cell line databases/resources CCLE; YD8_UPPER_AERODIGESTIVE_TRACT
Gene expression databases GEO; GSM887746
GEO; GSM888841