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Cellosaurus YD-8 (CVCL_L079)

[Text version]

Cell line name YD-8
Synonyms YD8
Accession CVCL_L079
Resource Identification Initiative To cite this cell line use: YD-8 (RRID:CVCL_L079)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 29.3 hours (PubMed=16264262).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations TP53 p.Arg273His (c.818G>A) (PubMed=16264262; CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.59
East Asian, North62.69
East Asian, South35.7
South Asian0
European, North0
European, South1.01
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 46Y
Category Cancer cell line
STR profile Source(s): KCLB; PubMed=16264262

Markers:
AmelogeninX
CSF1PO10
D3S135815.2 (KLCB)
15,16 (PubMed=16264262)
D5S81812
D7S82010,13
D8S117913,16
D13S3178,10
D16S5399,11
D18S5115,16
D21S1129,30
FGA24
Penta D13
Penta E12,15
TH017,9
TPOX8,11
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=16264262; DOI=10.1038/emm.2005.48
Lee E.J., Kim J., Lee S.A., Kim E.-J., Chun Y.-C., Ryu M.H., Yook J.-I.
Characterization of newly established oral cancer cell lines derived from six squamous cell carcinoma and two mucoepidermoid carcinoma cells.
Exp. Mol. Med. 37:379-390(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=23708675; DOI=10.3892/ijo.2013.1953
Oh J.-E., Kim J.-O., Shin J.-Y., Zhang X.-H., Won H.-S., Chun S.-H., Jung C.-K., Park W.-S., Nam S.-W., Eun J.-W., Kang J.-H.
Molecular genetic characterization of p53 mutated oropharyngeal squamous cell carcinoma cells transformed with human papillomavirus E6 and E7 oncogenes.
Int. J. Oncol. 43:383-393(2013)

PubMed=28053903; DOI=10.5125/jkaoms.2016.42.6.337
Jo D.-W., Kim Y.-K., Yun P.-Y.
The influence of p53 mutation status on the anti-cancer effect of cisplatin in oral squamous cell carcinoma cell lines.
J. Korean Assoc. Oral Maxillofac. Surg. 42:337-344(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections KCLB; 60501
Cell line databases/resources CCLE; YD8_UPPER_AERODIGESTIVE_TRACT
Cell_Model_Passport; SIDM01413
DepMap; ACH-000630
Biological sample resources BioSample; SAMN10988082
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887746
GEO; GSM888841
Other Wikidata; Q54995393
Polymorphism and mutation databases IARC_TP53; 21616
LiGeA; CCLE_283
Entry history
Entry creation06-May-2013
Last entry updated05-Jul-2019
Version number17