ID   YD-38
AC   CVCL_L083
SY   YD38
DR   ArrayExpress; E-MTAB-2770
DR   BioSample; SAMN10988077
DR   Cell_Model_Passport; SIDM01412
DR   DepMap; ACH-000762
DR   GEO; GSM887745
DR   GEO; GSM888840
DR   IARC_TP53; 21621
DR   IARC_TP53; 30220
DR   KCLB; 60508
DR   LiGeA; CCLE_758
DR   PharmacoDB; YD38_1682_2019
DR   Progenetix; CVCL_L083
DR   Wikidata; Q54995388
RX   PubMed=16264262;
RX   PubMed=22460905;
RX   PubMed=28053903;
RX   PubMed=30894373;
RX   PubMed=31068700;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Korean.
CC   Doubling time: 21.6 hours (PubMed=16264262).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Gly199Ter (c.595G>T); ClinVar=VCV000634672; Zygosity=Homozygous (DepMap).
CC   Omics: Deep exome analysis.
CC   Omics: Deep RNAseq analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis.
CC   Genome ancestry: African=0%; Native American=0.56%; East Asian, North=61.56%; East Asian, South=37.62%; South Asian=0%; European, North=0%; European, South=0.26% (PubMed=30894373).
ST   Source(s): KCLB; PubMed=16264262
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 8
ST   D16S539: 12,13
ST   D18S51: 14
ST   D21S11: 30,31
ST   D3S1358: 16
ST   D5S818: 14
ST   D7S820: 10,11
ST   D8S1179: 14
ST   FGA: 22,25
ST   Penta D: 8,12
ST   Penta E: 12,19
ST   TH01: 6,9
ST   TPOX: 8
ST   vWA: 14,17
DI   NCIt; C129857; Gingival squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Male
AG   67Y
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 16-12-21; Version: 22
//
RX   PubMed=16264262; DOI=10.1038/emm.2005.48;
RA   Lee E.J., Kim J., Lee S.A., Kim E.-J., Chun Y.-C., Ryu M.H.,
RA   Yook J.-I.;
RT   "Characterization of newly established oral cancer cell lines derived
RT   from six squamous cell carcinoma and two mucoepidermoid carcinoma
RT   cells.";
RL   Exp. Mol. Med. 37:379-390(2005).
//
RX   PubMed=22460905; DOI=10.1038/nature11003;
RA   Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A.,
RA   Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A.,
RA   Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J.,
RA   Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E.,
RA   Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J.,
RA   Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C.,
RA   Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C.,
RA   Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P.,
RA   Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L.,
RA   Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R.,
RA   Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.;
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=28053903; DOI=10.5125/jkaoms.2016.42.6.337;
RA   Jo D.-W., Kim Y.-K., Yun P.-Y.;
RT   "The influence of p53 mutation status on the anti-cancer effect of
RT   cisplatin in oral squamous cell carcinoma cell lines.";
RL   J. Korean Assoc. Oral Maxillofac. Surg. 42:337-344(2016).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//