ID   Man-12
AC   CVCL_L200
SY   MAN-12; Man 12; MAN12; Man12; CMFTe002-A
DR   BioSamples; SAMEA4760722
DR   hPSCreg; CMFTe002-A
DR   Wikidata; Q54903988
RX   PubMed=26607962;
RX   PubMed=28445466;
RX   PubMed=28583200;
CC   Group: Clinical grade hESC cell line.
CC   From: University of Manchester; Manchester; United Kingdom.
CC   Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC12-27.
CC   Omics: Array-based CGH.
CC   Omics: CNV analysis.
CC   Omics: Deep exome analysis.
CC   Omics: SNP array analysis.
CC   Donor information: Embryo is sibling to that giving rise to Man-11 (Cellosaurus=CVCL_L199).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-05-13; Last updated: 29-06-23; Version: 14
//
RX   PubMed=26607962; DOI=10.1038/srep17258;
RA   Canham M.A., Van Deusen A.L., Brison D.R., De Sousa P.A., Downie J.M.,
RA   Devito L.G., Hewitt Z.A., Ilic D., Kimber S.J., Moore H.D., Murray H.,
RA   Kunath T.;
RT   "The molecular karyotype of 25 clinical-grade human embryonic stem
RT   cell lines.";
RL   Sci. Rep. 5:17258-17258(2015).
//
RX   PubMed=28445466; DOI=10.1038/nature22312;
RA   Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C.,
RA   Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G.,
RA   Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A.,
RA   Eggan K.C.;
RT   "Human pluripotent stem cells recurrently acquire and expand dominant
RT   negative P53 mutations.";
RL   Nature 545:229-233(2017).
//
RX   PubMed=28583200; DOI=10.1186/s13287-017-0561-y;
RA   Ye J.-P., Bates N., Soteriou D., Grady L., Edmond C., Ross A., Kerby A.,
RA   Lewis P.A., Adeniyi T., Wright R., Poulton K.V., Lowe M., Kimber S.J.,
RA   Brison D.R.;
RT   "High quality clinical grade human embryonic stem cell lines derived
RT   from fresh discarded embryos.";
RL   Stem Cell Res. Ther. 8:128.1-128.13(2017).
//