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Cellosaurus CMT12 (CVCL_L329)

Cell line name CMT12
Synonyms CMT-12; Canine Mammary Tumor 12
Accession CVCL_L329
Resource Identification Initiative To cite this cell line use: CMT12 (RRID:CVCL_L329)
Comments Part of: FACC canine tumor cell line panel.
Doubling time: 19 hours (PubMed=27257868).
Omics: Transcriptome analysis.
Caution: On the basis of STR profile (PubMed=21908323; PubMed=27197945) CMT12 and CMT27 seem to originate from the same donor.
Disease Canine mammary carcinoma (NCIt: C124249)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Originate from same individual CVCL_1R41 ! CMT27
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=27197945

Markers:
Dog FHC2010235
Dog FHC2054151,176
Dog FHC2079271
Dog PEZ1115
Dog PEZ12277
Dog PEZ20176
Dog PEZ3113,119
Dog PEZ5103
Dog PEZ6176
Dog PEZ8233,244
Publications

PubMed=19130492; DOI=10.1002/jcb.22034
DeInnocentes P., Agarwal P., Bird R.C.
Phenotype-rescue of cyclin-dependent kinase inhibitor p16/INK4A defects in a spontaneous canine cell model of breast cancer.
J. Cell. Biochem. 106:491-505(2009)

PubMed=21801068; DOI=10.2460/ajvr.72.8.1097
Stokol T., Daddona J.L., Mubayed L.S., Trimpert J., Kang S.-K.
Evaluation of tissue factor expression in canine tumor cells.
Am. J. Vet. Res. 72:1097-1106(2011)

PubMed=21908323; DOI=10.1177/1040638711408064
O'Donoghue L.E., Rivest J.P., Duval D.L.
Polymerase chain reaction-based species verification and microsatellite analysis for canine cell line validation.
J. Vet. Diagn. Invest. 23:780-785(2011)

PubMed=23238983; DOI=10.1002/jcb.24476
Agarwal P., Sandey M., DeInnocentes P., Bird R.C.
Tumor suppressor gene p16/INK4A/CDKN2A-dependent regulation into and out of the cell cycle in a spontaneous canine model of breast cancer.
J. Cell. Biochem. 114:1355-1363(2013)

PubMed=27257868; DOI=10.1371/journal.pone.0156689
Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:E0156689-E0156689(2016)

PubMed=27197945; DOI=10.1111/vco.12192
Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

Cross-references
Gene expression databases GEO; GSM1974783
Other Wikidata; Q54813839