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Cellosaurus AG05397 (CVCL_L780)

[Text version]

Cell line name AG05397
Synonyms AG5397
Accession CVCL_L780
Resource Identification Initiative To cite this cell line use: AG05397 (RRID:CVCL_L780)
Comments Derived from sampling site: Thorax; skin.
Disease Down syndrome (NCIt: C2993)
Down syndrome (ORDO: Orphanet_870)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_D012 (DS1-iPS4)CVCL_EJ81 (WISCi005-A)CVCL_EJ83 (WISCi005-B)
CVCL_EJ82 (WISCi005-C)
Sex of cell Male
Age at sampling 1Y
Category Finite cell line

PubMed=17668376; DOI=10.1086/519248
Prandini P., Deutsch S., Lyle R., Gagnebin M., Delucinge Vivier C., Delorenzi M., Gehrig C., Descombes P., Sherman S., Dagna Bricarelli F., Baldo C., Novelli A., Dallapiccola B., Antonarakis S.E.
Natural gene-expression variation in Down syndrome modulates the outcome of gene-dosage imbalance.
Am. J. Hum. Genet. 81:252-263(2007)

PubMed=18691744; DOI=10.1016/j.cell.2008.07.041
Park I.-H., Arora N., Huo H., Maherali N., Ahfeldt T., Shimamura A., Lensch M.W., Cowan C., Hochedlinger K., Daley G.Q.
Disease-specific induced pluripotent stem cells.
Cell 134:877-886(2008)

PubMed=23716668; DOI=10.1073/pnas.1216575110
Weick J.P., Held D.L., Bonadurer G.F. III, Doers M.E., Liu Y., Maguire C., Clark A., Knackert J.A., Molinarolo K., Musser M.T., Yao L., Yin Y., Lu J., Zhang X., Zhang S.-C., Bhattacharyya A.
Deficits in human trisomy 21 iPSCs and neurons.
Proc. Natl. Acad. Sci. U.S.A. 110:9962-9967(2013)

PubMed=24119401; DOI=10.1016/j.molcel.2013.09.009
Chen J.-Y., Lin J.-R., Tsai F.-C., Meyer T.
Dosage of Dyrk1a shifts cells within a p21-cyclin D1 signaling map to control the decision to enter the cell cycle.
Mol. Cell 52:87-100(2013)

Cell line collections Coriell; AG05397
Ontologies CLO; CLO_0035217
Other Wikidata; Q54739981
Entry history
Entry creation06-May-2013
Last entry updated12-Mar-20
Version number11