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Cellosaurus PC-1.0 (CVCL_L901)

[Text version]
Cell line name PC-1.0
Synonyms PC-1-0; PC1.0
Accession CVCL_L901
Resource Identification Initiative To cite this cell line use: PC-1.0 (RRID:CVCL_L901)
Comments Transformant: ChEBI; CHEBI:131518; N,N-bis(2-hydroxypropyl)nitrosamine (Diisopropanolnitrosamine; DIPN; N-nitrosobis(2-hydroxypropyl)amine).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Mutation; UniProtKB; A0A1U7QTX5; Kras; Simple; p.Gly12Asp (c.35G>A); Zygosity=Unspecified (PubMed=2173932).
Disease Hamster pancreatic ductal adenocarcinoma (NCIt: C133090)
Species of origin Mesocricetus auratus (Golden hamster) (NCBI Taxonomy: 10036)
Hierarchy Parent: CVCL_L900 (PC-1 [Hamster])
Sex of cell Male
Age at sampling 8W
Category Cancer cell line
Publications

PubMed=2173932; DOI=10.1002/mc.2940030510
Fujii H., Egami H., Chaney W.G., Pour P.M., Pelling J.
Pancreatic ductal adenocarcinomas induced in Syrian hamsters by N-nitrosobis(2-oxopropyl)amine contain a c-Ki-ras oncogene with a point-mutated codon 12.
Mol. Carcinog. 3:296-301(1990)

PubMed=1530768
Kumble K.D., Hirota M., Pour P.M., Vishwanatha J.K.
Enhanced levels of annexins in pancreatic carcinoma cells of Syrian hamsters and their intrapancreatic allografts.
Cancer Res. 52:163-167(1992)

PubMed=8382114; DOI=10.1093/carcin/14.2.259
Hirota M., Egami H., Corra S., Fujii H., Chaney W.G., Rizzino A., Pour P.M.
Production of scatter factor-like activity by a nitrosamine-induced pancreatic cancer cell line.
Carcinogenesis 14:259-264(1993)

PubMed=8863680
Erill N., Cuatrecasas M., Sancho F.J., Farre A., Pour P.M., Lluis F., Capella G.
K-ras and p53 mutations in hamster pancreatic ductal adenocarcinomas and cell lines.
Am. J. Pathol. 149:1333-1339(1996)

Cross-references
Anatomy/cell type resources BTO; BTO:0002746
Encyclopedic resources Wikidata; Q54938385
Entry history
Entry creation06-May-2013
Last entry update29-Jun-2023
Version number13