Home  |  Contact

Cellosaurus PathHunter U2OS HTR2C(VSV) beta-arrestin (CVCL_LA61)

[Text version]

Cell line name PathHunter U2OS HTR2C(VSV) beta-arrestin
Accession CVCL_LA61
Resource Identification Initiative To cite this cell line use: PathHunter U2OS HTR2C(VSV) beta-arrestin (RRID:CVCL_LA61)
Comments Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Transfected with: HGNC; 5295; HTR2C (with p.Ile156Val, p.Asn158Ser and p.Ile160Val).
Transfected with: HGNC; 712; ARRB2.
Derived from sampling site: Bone; tibia.
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Cell line collections DiscoverX; 93-0921C3
Other Wikidata; Q54938188
Entry history
Entry creation22-Aug-2017
Last entry update12-Mar-2020
Version number5