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Cellosaurus PathHunter U2OS Keap1-NRF2 Nuclear Translocation (CVCL_LA64)

[Text version]

Cell line name PathHunter U2OS Keap1-NRF2 Nuclear Translocation
Accession CVCL_LA64
Resource Identification Initiative To cite this cell line use: PathHunter U2OS Keap1-NRF2 Nuclear Translocation (RRID:CVCL_LA64)
Comments Characteristics: PathHunter nuclear translocation cell lines co-express a target protein tagged with a beta-galactosidase fragment (Enzyme Donor=ED) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the nucleus. Complementation of the ED and EA enzyme fragments result into a catalytically active enzyme that generate a chemiluminescent signal.
Transfected with: HGNC; 23177; KEAP1.
Transfected with: HGNC; 7782; NFE2L2.
Derived from sampling site: Bone; tibia.
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Cell line collections DiscoverX; 93-0821C3
Other Wikidata; Q54938192
Entry history
Entry creation22-Aug-2017
Last entry update12-Mar-2020
Version number4