| Cell line name | PathHunter U2OS rFFAR1 beta-arrestin |
|---|---|
| Accession | CVCL_LB27 |
| Resource Identification Initiative | To cite this cell line use: PathHunter U2OS rFFAR1 beta-arrestin (RRID:CVCL_LB27) |
| Comments | Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal. Transfected with: RGD; 628613; Ffar1. Transfected with: HGNC; 712; ARRB2. Derived from sampling site: Bone; tibia. |
| Disease | Osteosarcoma (NCIt: C9145) Osteosarcoma (ORDO: Orphanet_668) |
| Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
|
| Hierarchy | Parent: CVCL_0042 (U2OS) |
| Sex of cell | Female |
| Age at sampling | 15Y |
| Category | Cancer cell line |
| Cross-references | |
| Cell line collections | DiscoverX; 93-0976C3 |
| Other | Wikidata; Q54938286 |
| Entry history | |
| Entry creation | 22-Aug-2017 |
| Last entry update | 12-Mar-2020 |
| Version number | 4 |