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Cellosaurus SW48 KRAS (G12R/+) (CVCL_LC94)

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Cell line name SW48 KRAS (G12R/+)
Synonyms KRAS (G12R/+) SW48
Accession CVCL_LC94
Resource Identification Initiative To cite this cell line use: SW48 KRAS (G12R/+) (RRID:CVCL_LC94)
Comments Characteristics: Heterozygous knockin of a KRAS activating mutation.
Sequence variations Heterozygous for KRAS p.Gly12Arg (c.34G>C).
Homozygous for ACVR2A p.Lys437fs*5 (c.1310delA) (from parent cell line).
APC p.Arg2714Cys (c.8140C>T) (from parent cell line).
Heterozygous for CTNNB1 p.Ser33Tyr (c.98C>A) (from parent cell line).
Homozygous for TGFBR2 p.Lys128Serfs*35 (c.383delA) (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1724 (SW48)
Sex of cell Female
Age at sampling 83Y
Category Cancer cell line
Web pages https://www.horizondiscovery.com/human-kras-g12r-sw48-cell-line-hd-103-010
Cross-references
Other Wikidata; Q54971130