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Cellosaurus SW48 KRAS (G12V/+) (CVCL_LC95)

[Text version]

Cell line name SW48 KRAS (G12V/+)
Synonyms KRAS (G12V/+) SW48
Accession CVCL_LC95
Resource Identification Initiative To cite this cell line use: SW48 KRAS (G12V/+) (RRID:CVCL_LC95)
Comments Characteristics: Heterozygous knockin of a KRAS activating mutation.
Sequence variations Heterozygous for KRAS p.Gly12Val (c.35G>T).
Homozygous for ACVR2A p.Lys437fs*5 (c.1310delA) (from parent cell line).
APC p.Arg2714Cys (c.8140C>T) (from parent cell line).
Heterozygous for B2M p.Ser14fs*29 (c.41_44delCTCT) and p.Glu67fs (c.200delA) (from parent cell line).
Heterozygous for CTNNB1 p.Ser33Tyr (c.98C>A) (from parent cell line).
Homozygous for TGFBR2 p.Lys128Serfs*35 (c.383delA) (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1724 (SW48)
Sex of cell Female
Age at sampling 83Y
Category Cancer cell line
Web pages https://www.horizondiscovery.com/human-kras-g12v-sw48-cell-line-hd-103-007
Cross-references
Other Wikidata; Q54971134
Entry history
Entry creation22-Aug-2017
Last entry updated24-May-2019
Version number4