Cell line name |
SW48 NRAS (Q61H/+) |
Synonyms |
NRAS (Q61H/+) SW48 |
Accession |
CVCL_LD01 |
Resource Identification Initiative |
To cite this cell line use: SW48 NRAS (Q61H/+) (RRID:CVCL_LD01) |
Comments |
Population: Caucasian. Characteristics: Heterozygous knockin of a NRAS activating mutation. Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
Sequence variations |
- Mutation; HGNC; 173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 583; APC; Simple; p.Arg2714Cys (c.8140C>T); ClinVar=VCV000231255; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; 914; B2M; Simple; p.Ser14fs*29 (c.41_44delCTCT); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 914; B2M; Simple; p.Glu67fs (c.200delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 2514; CTNNB1; Simple; p.Ser33Tyr (c.98C>A); ClinVar=VCV000017577; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 7989; NRAS; Simple_edited; p.Gln61His (c.183A>T); ClinVar=VCV000373003; Zygosity=Heterozygous; Note=By method not specified (Horizon_Discovery=HD+103-035).
- Mutation; HGNC; 11773; TGFBR2; Simple; p.Lys128Serfs*35 (c.383delA); ClinVar=VCV000477546; Zygosity=Homozygous (from parent cell line).
|
Disease |
Colon adenocarcinoma (NCIt: C4349) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_1724 (SW48) |
Sex of cell |
Female |
Age at sampling |
83Y |
Category |
Cancer cell line |
Cross-references |
Cell line collections (Providers) |
Horizon_Discovery; HD+103-035
|
Cell line databases/resources |
cancercelllines; CVCL_LD01
|
Encyclopedic resources |
Wikidata; Q54971140
|
Entry history |
Entry creation | 22-Aug-2017 |
Last entry update | 30-Jan-2024 |
Version number | 13 |
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