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Cellosaurus UOXFi007-A (CVCL_LE37)

[Text version]

Cell line name UOXFi007-A
Synonyms MK002-4; iPS-MK002-4
Accession CVCL_LE37
Resource Identification Initiative To cite this cell line use: UOXFi007-A (RRID:CVCL_LE37)
Comments From: University of Oxford; Oxford; United Kingdom.
Omics: Genome sequenced.
Omics: Transcriptome analysis.
Derived from sampling site: Skin; dermis.
Sequence variations Mutation; HGNC; 18618; LRRK2; Simple; p.Gly2019Ser (c.6055G>A); ClinVar=VCV000001940; Zygosity=Heterozygous (PubMed=28096185).
Disease Parkinson's disease (NCIt: C26845)
Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A8Y3 (MK002)
Sex of cell Female
Age at sampling 72Y
Category Induced pluripotent stem cell
Publications

PubMed=28096185; DOI=10.1093/hmg/ddw412
Sandor C., Robertson P., Lang C., Heger A., Booth H., Vowles J., Witty L., Bowden R., Hu M.T., Cowley S.A., Wade-Martins R., Webber C.
Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.
Hum. Mol. Genet. 26:552-566(2017)

Cross-references
Cell line collections EBiSC; UOXFi007-A
ECACC; 66540556
Cell line databases/resources hPSCreg; UOXFi007-A
Biological sample resources BioSamples; SAMEA103988274
Encyclopedic resources Wikidata; Q54991451
Gene expression databases GEO; GSM2055810
GEO; GSM2055815
Entry history
Entry creation22-Aug-2017
Last entry update16-Dec-2021
Version number9