ID   EDi001-A-2
AC   CVCL_LE52
SY   AST22-1KO-3; AST23-1KO-3; AST-22_SNCAKO Clone 3; AST-23_SCAKO Clone 3
DR   BioSamples; SAMEA3323846
DR   EBiSC; EDi001-A-2
DR   ECACC; 66540167
DR   hPSCreg; EDi001-A-2
DR   Wikidata; Q54831973
CC   From: University of Edinburgh; Edinburgh; United Kingdom.
CC   Population: Caucasian.
CC   Characteristics: The donor of the original cell line has 4 copies of SNCA. This edited cell line clone has 1 of the 4 alleles KO by CRISPR/Cas9 (hPSCreg=EDi001-A-2).
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 11138; SNCA (Note=1 of 4 alleles).
CC   Discontinued: ECACC; 66540167; true.
CC   Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C198604; Parkinson disease 4, autosomal dominant
DI   ORDO; Orphanet_411602; Hereditary late-onset Parkinson disease
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_AW97 ! EDi001-A
SX   Female
AG   55Y
CA   Induced pluripotent stem cell
DT   Created: 22-08-17; Last updated: 30-01-24; Version: 12
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